Sentence examples for development of medication from inspiring English sources
Complicated MOH patients, especially those who already had a high headache frequency before development of medication overuse and who had tried more than one preventive treatment in the past, probably need early prophylaxis (clinical experience-based recommendation).
CM has been associated with a high intake of abortive medications with estimated analgesic overuse in 50 80% of patients with CM that may lead to the development of medication overuse headache (MOH) [47].
It is estimated that around 50 80 % of patients with CM referring to headache clinics show analgesic overuse that may lead to the development of medication overuse headache (MOH) [7].
Long-term frequent use of triptans, as may be needed for cCH management, can in turn lead to the development of medication overuse headache [29, 30], which, although rare, has been reported in patients with CH [31, 32].
Even with the development of medication protocols, treatment may still vary among physicians.
This fact may herald a new era for the development of medication with higher specificity and efficacy for this condition.
This will stimulate the development of medications to treat the unmet medical need generated by the aesthetic discomfort caused by HOA.
only for "excessive sleepiness associated with narcolepsy" under the Orphan Drug Act, legislation designed to encourage development of medications needed only by small numbers of patients.
Factors associated with development of medication-overuse headache (MOH) in migraine patients are not fully understood, but with respect to prevention, the ability to predict the onset of MOH is clinically important.
Combination analgesics, triptans, muscle relaxants and opioids should not be used, and it is crucial to avoid frequent and excessive use of simple analgesics to prevent the development of medication-overuse headache.
