HSC lines were transplanted into irradiated mice to model the normal development of immunity and establishment of immune homeostasis.
Serum antibody responses against chlamydiae were examined to test the vault immunization scheme for development of immunity.
These immune mediators play crucial roles in the development of immunity against a variety of pathogens, but their role in helminthic infections is less well understood [ 32, 33].
Intranasal immunization using peptides contained within vault nanoparticles allows development of immunity capable of significantly limiting a bacterial infection in a mucosal tissue.
Lymphocytes are concerned with the development of immunity.
The development of immunity toward an antigen is called sensitization.
These results demonstrate that the T cells produced in the thymus and transported to the lymphoid tissues are crucial elements in the development of immunity.
It was concluded that dietary tannins may reduce the efficacy of anticoccidial vaccines and alter the proper development of immunity against the disease.
Targeting antigen to immune cells via PAMP-modified biomaterials is a new strategy to control the subsequent development of immunity and, in turn, effective vaccination.
As we work to identify principles regulating the host:environment interactions that modulate the immune system, we seek to deepen our understanding of how this may impact the development of immunity to infection and efficacy of vaccination.
Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation.
