Sentence examples for development of hyperinsulinemia from inspiring English sources
Development of hyperinsulinemia.
Mice deficient in A-FABP are protected from development of hyperinsulinemia, hyperglycemia, and insulin resistance [ 3].
Interestingly, this preceded development of hyperinsulinemia and treatment with the insulin sensitive drug rosiglitazone caused downregulation of these genes.
Moreover, mice deficient in AFABP are protected from development of hyperinsulinemia, hyperglycemia, and insulin resistance (8, 9).
Mice deficient in A-FABP are resistant to the development of hyperinsulinemia, hyperglycemia and insulin resistance [ 18].
In his original description, Reaven (1) considered the development of hyperinsulinemia as a compensative phenomenon in response to insulin resistance to be the core and fundamental sign of metabolic syndrome.
The present results are consistent, however, with the development of hyperglycemia, hyperinsulinemia, hypertriglyceridemia, and increased body weight in transgenic mice overexpressing hepatic GK (25).
The KKAy mice represent a model for obesity and type 2 diabetes, with spontaneous development of hyperglycemia, hyperinsulinemia, glucose intolerance, and obesity [22,23].
It is also considered to be an important risk factor for the development of obesity, hyperinsulinemia, hypertension, dyslipidemia and atherosclerosis [ 5].
Long-term administration of time-release melatonin pellets (1.1 mg/day for 30 weeks) reduced the development of hypertriglyceridemia, hyperinsulinemia, and hyperleptinemia, and restored normal ratios of 20 3n 6/20 4n 6 phospholipids in a rat model of diabetes.
Biguanides also inhibits the development of atherosclerosis, reduces hyperinsulinemia in men with coronary artery disease.
