Sentence examples for development of human hepatocyte from inspiring English sources

The shortage of organ donors has impeded the development of human hepatocyte transplantation.

In particular, we examine the development of human hepatocyte cell lines, strategies to stabilize the hepatocyte phenotype in vitro, and emphasize the importance of the cellular microenvironment in bioreactor design.

Our series is the largest reported of human hepatocyte isolations from cirrhotic livers (n = 55).

The recent developments in the isolation, culturing, and cryopreservation of human hepatocytes, and the application of the cells in drug development are reviewed.

Applications of human hepatocytes in drug development include the evaluation of metabolic stability, metabolite profiling and identification, drug drug interaction potential, and hepatotoxic potential.

Therefore, we examined the cytotoxicity of the Cu II) compounds 1 6 in primary cultures of human hepatocytes (Table 1).

The importance of the results achieved on a panel of human cancer cell lines has been also emphasized by the results on primary culture of human hepatocytes.

We concur with previous authors that normal resected tissue is a good source of human hepatocytes.

These data illustrate that aptamer ZE2 may indeed block and inhibit viral infection of human hepatocytes.

Dedifferentiation of human hepatocytes in culture is problematic.

However, this approach is limited by the shortage of reproducible sources of human hepatocytes [ 1].