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Understanding the regulation of inflammatory pathways in the brain during infection and the molecular events linked to control of inflammation is critical to preventing the development of HIV encephalitis and cognitive changes observed in HIV-infected individuals.
Highly Active Antiretroviral Therapy (HAART) has proven remarkably effective in controlling the development of HIV.
Understanding the social networks of MSM may support the development of HIV prevention strategies for this unique population.
She led the development of several international programs focused on development of HIV care and treatment programs in several resource-limited countries.
Differentiation marker, multifunctionality and magnitude analyses of specific-CD8+ memory T cells are crucial to improve development of HIV vaccines designed to generate cell-mediated immunity.
These studies established proof of concept that F3284-8495 could be used as a favorable chemical scaffold for development of HIV RNase H inhibitors.
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FIV vaccine development has closely mirrored and occasionally surpassed the development of HIV-1 vaccine, leading to first licensed technology.
In the future development of HIV-1 vaccines by rational design, a more effective live virus vector or multiple antigens should be chosen to facilitate the process of neutralizing antibody maturation.
There is an urgent need for a vaccine capable of preventing HIV infection or the development of HIV-related disease.
Thus, native-like trimers represent a promising starting point for the development of HIV-1 vaccines aimed at inducing bNAbs.
She conducts research on the development of HIV-related mental health interventions focused on traumatic stress and coping.
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