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Lack of accurate assessment of the experimental methods themselves hinders both interpretation of the results and further development of genomic techniques.
With the development of genomic techniques and an expansion in our understanding of the normal and diseased 'methylome', the prospect of a diagnostic methylation signature for each subtype of cancer becomes a genuine possibility.
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Although these estimates seem low as compared to other AS studies (see Discussion for details), we may expect a rapid growth in the data abundance in the near future due to the fast development of novel genomic techniques (e.g. [20]), which will help fully understand the effects of this mechanism.
Suppose we had deep knowledge of imprinting in a breadth of taxa for which we had a reliable phylogeny, which due to the development of novel genomic techniques may not be far off, what would this mean for our understanding of the evolution of imprinting?
The past decade has seen accelerated development of genomic and transcriptomic techniques.
Understanding sexual reproduction is at the forefront of plant research and has benefited immensely from the development of genomic, transcriptomic and proteomics techniques in recent decades.
The retroviral insertions act as 'tags' for identifying the mouse genes that are mutated by insertional mutagenesis, and sequencing of the mouse genome and the development of high-throughput genomic techniques have made it possible to identify thousands of insertions in a single screen.
The availability of complete genome sequences, the advances in microarray technologies, and the development of novel functional genomic techniques such as 'chromatin profiling' facilitate dissection of the interplay among transcriptional networks and reveals chromosome organization in vivo.
Developments in genomic techniques have provided insight into the remarkable genetic complexity of malignant tumours.
Breeding efforts, therefore, require the development of genomic resources for fertile mint species.
Over the past several years, we have made considerable progress in the development of genomic tools for CHO.
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