Sentence examples for development of experimental systems from inspiring English sources
Animal models of uveal melanoma have undergone many improvements, leading to the development of experimental systems that better represent the disease in human beings.
While studies of cultured cells have led to new insights into biological control, greater understanding of human pathophysiology requires the development of experimental systems that permit analysis of intercellular communications and tissue-tissue interactions in a more relevant organ context.
Central to this endeavour will be the development of experimental systems and approaches by which theories of cancer evolution can be effectively tested.
The black box of the early molecular changes in ovarian carcinogenesis is being interpreted by the development of experimental systems employing immortalised human OSE cells.
In addition, the implications for the development of experimental systems are profound, suggesting that two-dimensional, and even three-dimensional, tissue-culture experiments that focus solely on epithelial cells could be missing a central mechanism of carcinogenesis.
This is due to limited access to human tissues, as well as to lack of experimental systems to study human pancreatic development.
Development of novel experimental systems.
Schematic diagram of experimental system.
a Schematic of experimental system and b experimental setup.
(A ) Cartoon schematic of experimental system.
The most likely interpretation is that replicative senescence is initiated in a p53-dependent manner when the integrated signalling from DDR+ telomeres reaches a threshold level, but formal proof will require the development of an experimental system to induce limited numbers of non-fusogenic, DDR+ telomeres in human cells.
