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By contrast the leather-skinned titans that Steven Spielberg brought to life in 1993's original Jurassic Park still, despite the vertiginously accelerated development of effects technology in the intervening 20 years, hold their own against contemporary creature effects.
Inhalation studies are designed to determine the nature, onset, and duration of adverse effects and hazards from acute, short-term repeated and long-term repeated respiratory exposure; factors influencing the development of effects; and the efficacy of antidotal treatment.
In this framework, the contextual factors are considered to be the necessary input for the development of effects of medical testing on patients.
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Although it may have been frustrating for Hans Toni that for a long time effect models in environmental risk assessment were only reluctantly accepted, it certainly will enjoy him that now his students play an active role in the promoting and further development of effect models as tools for higher-tier risk assessment [16 18].
Thus, anxiety [ 28] and depression may be relevant in the development of nocebo effects and non -specific side effects [ 14].
However, if lipase inhibition does produce beneficial changes in behavior through GI-related side effects, the development of side effect-free lipase inhibitors will be pointless.
32 Initial study medication doses of 2 mg were gradually titrated to an effective therapeutic response or the development of adverse effects.
The severity of late effects was scored from 0 to 4, whereby the development of side effects of scores ⩾2 was considered to indicate late normal tissue complications.
According to these authors, exposure duration is critical to the development of neurocognitive effects after organic and inorganic lead exposure, whereas exposure intensity is more critical for the development of neurocognitive effects following exposure to organic solvents.
Topiramate was started because of the development of side effects of indomethacin.
None of the baseline variables predicted a favorable response to BoNT-A treatment or the development of adverse effects.
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