Sentence examples for development of derivatives from inspiring English sources

A lot of effort is therefore put into the development of derivatives of BetA with the goal to develop even more powerful compounds and to achieve better solubility for enhanced in vivo administration [1] [3].

He said that the development of derivatives had gone beyond simply covering risk, which had been their raison d'être.

LASSBio-1755 is a new cycloalkyl-N-acylhydrazone parent compound designed for the development of derivatives with antinociceptive and anti-inflammatory activities.

On the basis of these results, information was acquired for additional development of derivatives with different linkers and better solubility for in vivo evaluation.

Consequently, this has led to the development of derivatives such as irinotecan.

The pronounced activity of harmonine against mycobacteria together with activity against an MRSA strain is indicative for a novel mode of action, which might be exploited by the development of derivatives less toxic to human cells.

Interest in these data is widespread and ongoing, as evidenced by published analyses of the data and the development of derivative products.

Thus, the development of derivative free optimization algorithms has long been studied and the deterministic global search algorithm DIRECT (DIviding a hyper-RECTangle) was suggested.

Thus, although the proportion of hybrids may be small in relation to the total tumor mass, the spontaneity of cell fusion, and the survival and growth of the hybrids may cause the development of derivative clones that might have important clinical implications.

In 1923, its active component was identified as the guanidine derivative galegine, leading to the development of biguanide derivatives in the 1950s.

A basic understanding of the tumoritropic behaviour of hypericin would not only support the construction of hypericin derivatives with optimised PDT characteristics, but also sustain the development of labelled derivatives to extend the application of hypericins beyond the field of PDT.