Sentence examples for development of dependence from inspiring English sources
The development of dependence has been conceptualized as a neurobehavioral disorder that advances from impulsive drug use to compulsive drug abuse.
These changes could help protect individuals from the damaging effects of the drug, prevent the development of dependence in new users, and maybe even help our favorite Hollywood stoners remember where they left their car.
The individual differences at genetic, personality, affective, and cognitive levels relate to the development of dependence and influence the effects of pharmacological and psychological interventions.
In contrast, FAAH mice showed identical withdrawal responses as wild-type mice under a variety of conditions, suggesting that the absence of this enzyme across the development of dependence and during rimonabant challenge does not affect withdrawal responses.
Together, these studies suggest that low D2 receptor binding may serve as a risk factor for the development of dependence, although other studies have shown that cocaine self-administration itself also produces a decrease in D2 receptor binding (Nader et al, 2006).
"It was some of our opiate work that first sensitized me pun intended to the idea that the [brain's] reward system was compromised" in alcohol dependence, he says, "whereas it was the alcohol work that sensitized me to the idea that the stress system plays a key role in the development of dependence on non-alcohol drugs".
Development of alcohol dependence, a chronic and relapsing disease, largely depends on the effects of alcohol on the brain reward systems.
Harmful drinking frequently originates during adolescence, which increases the risk of developing alcohol-related problems later during adulthood [1] and might facilitate the development of alcohol dependence.
Another aspect may be the development of emotional dependence.
Role of conditioning factors in the development of drug dependence.
Liu IC, Blacker DL, Xu R, Fitzmaurice G, Lyons MJ, Tsuang MT. Genetic and environmental contributions to the development of alcohol dependence in male twins.
