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Improvements in trial design, including development of consortia for the conduct of national and international multicenter studies and use of standardized classification and outcome measures coupled with the emergence of newer biologic, immunomodulatory, and small molecule agents, hopefully will result in the addition of disease-modifying agents to the armamentarium.
These concerns have encouraged the field to grow in many new directions, including the development of consortia and large-scale data collection projects and the use of novel methods (e.g., polygenic approaches, machine learning) that enhance the quality of imaging genetic studies but also introduce new challenges.
As much of the research is specific to a single pathogen/host system, the way ahead in bioherbicide research would appear to be the development of consortia or research nodes in which scientists and business people with backgrounds in the discovery, development and commercialization of biopesticides work collaboratively on a number of projects.
This might involve the development of consortia of cohort investigators across varied countries who would pool harmonized data across cohorts, and examine multiple issues including but not limited to competing risk analyses of non-AIDS and HIV-related mortality, and better investigation of potential sources of confounding.
Similar(56)
With the application of slow release fertilizers, design of immobilization techniques and development of microbial consortia, scale-up studies and in situ applications have been possible.
DNA was also extracted from each fermenter weekly and metagenomics will be used to examine the temporal and spatial development of microbial consortia.
Although the development of large consortia of thousands of subjects may obviate some of the issues that have contributed to non-replication of previous COPD genetic studies (such as power limitations germane to smaller studies), the inclusion of data from a large number of studies presents unique challenges and opportunities.
We found the method particularly useful as a diagnostic tool to follow the dynamic development of the microbial consortia in an agricultural biogas plant in terms of fragment number and quantity as well as their diversity and the possible dominance of the respective consortia by individual ARISA fragment types.
The restructuring of the health service with development of GP commissioning consortia is likely to lead to further development of community based services for chronic conditions.
As demonstrated here and in different studies [ 18], the development of synthetic microbial consortia using species with different characteristics (e.g. different growth rate or volume) yields systems with intriguing dynamics, such as oscillations.
Tools and methods are also emerging to facilitate the development of stable and robust consortia.
Related(16)
promotion of consortia
development of organization
production of consortia
development of assemblage
development of foundation
development of venture
development of contractor
development of consolidation
development of collaborative
development of ring
development of cluster
development of corporations
development of syndicates
development of trusts
development of businesses
development of pools
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