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The results of this study should encourage the development of combined preoperative and intraoperative methods (e.g. a combination of PET-CT using a positron emitter-labelled tracer for preoperative PET-CT with a 99mTc-labelled and/or ICG-labelled tracer for intraoperative detection) to improve the current SLN procedure.
Despite the development of combined therapeutic modalities for CRC treatment, including surgical operation and combination of chemotherapy and adjuvant therapy, the overall prognosis of CRC remains unsatisfactory and the 5-year survival rate of CRC patients with metastasis is still under 10% [ 8, 9].
The rational drug design, chemical syntheses, antitumor activity, mechanism of action, and development of combined chemotherapy regimens, including a DNA repair inhibitor, are discussed.
There are currently several approaches to the development of combined PET/MRI systems, all of which need to address adverse interactions between the two systems.
The paper also includes a discussion on the contribution the ecotoxicological background on mixture toxicity may have to the development of combined chemical treatments for pest mitigation.
The results indicate that a feed-in-tariff is required to support the development of combined heating, cooling, and power systems, which not only improves the economic performance of the system, but also increases the utilisation of more efficient generation technologies such as combined cooling, heat and power systems.
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This has prompted the development of combining LAMA+LABA as fixed-dose combinations (FDCs) [ 1].
The scope of this review is to move from basics to the latest developments of combined techniques using ultrasound for triggering drug release.
Novel developments of combined microRNA/siRNA pharmacological approaches will be discussed and most recently data about MXR34, the first-tested microRNA drug will be described.
The development of a combined EEG and fMRI technique has increased in the past few years.
Here at Princeton, working with his advisor Dr. Mikhail Shneider, Christopher is involved in the development of a combined laser-microwave diagnostic, Radar REMPI (resonance-enhanced multi-photon ionization).
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