Sentence examples for development of chromosomal from inspiring English sources

This finding suggests the deregulation epigenetic components at the kinetochore complex could lead to chromosome defects and the development of chromosomal instability.

The selection of a key thiolase (bktB) and thioesterase (ydiI) in combination with previously established core β-oxidation reversal enzymes, as well as the development of chromosomal expression systems for the independent control of pathway enzymes, enabled the generation of C6 C10 carboxylic acids and provided a platform for vector based independent expression of ω-functionalization enzymes.

Our studies using these cells indicate that polyploidy induced by Pim-1 can promote the development of chromosomal abnormalities and tumorigenicity in human prostate and mammary epithelial cells.

Disorders of sex development (DSD) comprise a large number of cases in which development of chromosomal, gonadal or anatomical sex is atypical [1].

It is noteworthy that non-homologous-mediated end joining of DNA DSB was proposed to reverse apoptosis, albeit at low frequency, leading to the development of chromosomal translocations, particularly those linked to t-AML [53], [54].

Binding of HR-E6 to MCM7 leads to the development of chromosomal abnormalities which promote DNA damage.

The precise roles of these factors in the development of chromosomal instability and retro-transposition require further study.

Unrepaired DNA ends might contribute to the development of chromosomal translocations by acting as transposable elements (Hall, 2006a).