Sentence examples for development of caa from inspiring English sources
Oxidized Aβ peptides were demonstrated in all 10 AD cases with CAA but in only one of six without CAA, raising the possibility that the presence of oxidized Aβ promotes the development of CAA (for example, by interfering with the perivascular drainage or endothelial uptake and transport of the peptide) or that CAA increases oxidative stress.
In this study, we screened genetic variants of 9 SNX genes in relation to KD with CAA formation and identified a SNP in SNX24 that correlates with the development of CAA formation in Taiwanese children of Han Chinese ethnic background with KD.
Younger patient age, particularly less than 1 year of age, male sex and delayed diagnosis and treatment have also been associated with development of CAA [1, 17, 18].
Such a retention of Aβ may also contribute to the development of CAA and Alzheimer's disease.
Thus, SVD-related alterations of the BBB may contribute to the development of CAA and possibly of parenchymal Aβ deposition.
Longer fever duration and the delay of IVIG treatment seem to be risk factors for the development of CAA in patients with KD.
To assess whether IVIG+CsA combination therapy as the primary treatment is superior to the standard IVIG treatment in preventing the development of CAAs in paediatric patients with severe KD.
Therefore, reduction in cerebral clearance of Aβ is considered one of the major factors contributing to Aβ accumulation and subsequent development of late-onset CAA and AD.
These data suggest that GRIK1 may be a potential susceptibility locus involved in the development of KD with CAA complications.> -wrap-foot> position pofindividualndividual SNPs was based on the NCBI Assembly database: GRCH38 version.
In this study, we screened the entire glutamate receptor family including the iGluRs and mGluRs (GRIK, GRIA and GRM gene families) and identified another member, namely GRIK1, that may be involved in the development of KD-associated CAA complications in Taiwanese children of Han Chinese ethnic background.
Morphologically, two types of CAA can be distinguished: CAA with capillary involvement (CAA-type 1) and CAA lacking capillary Aβ deposition (CAA-type 2) [ 130].
