Sentence examples for development of allergen from inspiring English sources

In fact, the sausage contained admixtures of 11 plant species (Additional file 3) to enable its use in the development of allergen detection methods.

Muñoz-Furlong believes that the next step in the development of allergen labeling should be to create binding guidelines for what is currently the voluntary use of "precautionary labeling," which warns of the possibility that an allergen might be present as the result of shared production processes.

One of the major factors in the development of allergen-induced lung pathophysiology is inflammatory cell infiltration to the airways.

administration of house dust mite extract (HDM), a natural aeroallergen, on subsequent development of allergen-induced AHR.

To assess whether genetic differences responsible for conferring susceptibility to the development of allergen-induced AHR are associated with changes in the balance of mDCs and pDCs taking up allergen at the time of sensitization, A/J and C3H mice were given a single i.t.

We demonstrate that genetic susceptibility to the development of allergen-induced AHR is the result of a pulmonary environment which, following allergen exposure, allows allergen presentation by mDCs expressing high levels of co-stimulatory molecules, and producing a Th17-promoting cytokine profile (IL-23 and IL-6).

Collectively these data demonstrate that the lung environment present in asthma-resistant mice promotes robust pDC allergen uptake, activation, and limits Th17-skewing cytokine production responsible for driving pathologic T cell responses central to the development of allergen-induced airway hyperresponsiveness.

Using this model, we demonstrate that following allergen exposure in susceptible hosts, allergen uptake is predominantly by pulmonary mDCs capable of high level co-stimulatory molecule expression and the production of Th17-promoting cytokines production (IL-6, IL-23), and that these factors are critical for the development of allergen-induced airway hyperresponsiveness.

Progress in the development of allergen-SIT has been hindered by a lack of understanding of the underlying immunological mechanisms.

Furthermore, the most relevant components can be identified to aid in the development of allergen-specific treatments and preventative strategies.

To avert the development of allergen-specific Th2 responses in atopic individuals is an important strategy in the prevention and cure of IgE-mediated allergic disorders.