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The development of alignment strategies has received a great deal of attention in recent literature.
Further development of alignment software would be desirable to facilitate the application of NGS in mtDNA forensic genetics.
In addition, our anchoring procedure can be used to obtain information for the further development of alignment algorithms.
Authors state that short-read alignment is no longer a bottleneck and consider future development of alignment algorithms with respect to emerging long sequence reads.
Efficiently aligning long reads against a long reference sequence like the human genome poses a new challenge to the development of alignment tools.
For the further development of alignment algorithms, it is crucial to find out which one of these reasons is to blame for mis-alignments produced by existing software programs.
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Lastly, devising clever ways to provide all such classes of variants as a 'searchable space' for sequence data alignment remains a significant challenge, as does the development of sequence alignment algorithms that facilitate the analysis of structurally complex loci.
The latter result has important consequences for the further development of our alignment approach: it seems worthwile to develop more efficient algorithms for the optimisation problem that arises in the context of the DIALIGN algorithm.
Finally, we propose new directions for the future development of multiple alignment construction and analysis methods.
In this study, we show that the simple application of a continuous strain to a fibrin gel facilitates the development of fibril alignment and bundle-like structures in the fibrin gel in the direction of the applied strain.
The development of 1D alignment methods has allowed these spectra to be analyzed with increasing accuracy and resolution.
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