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We have given several examples demonstrating that fouling organisms are influenced in their initial surface colonization behaviour, and the subsequent development of adhesion strength, by nano- and micro-scale-engineered coating designs.
Hallmarks of the myofibroblast are secretion of extracellular matrix, development of adhesion structures with the substrate, and formation of contractile bundles composed of actin and myosin.
The effect of the welding parameters (energy and force) and the thickness of a thermoplastic film, applied as an upper ply in the composite lay-up, on the development of adhesion strength, was investigated.
This concept may lead to the development of adhesion systems which allow precise control of the pull-off force as a function of preload.
If the capsulorhexis is too large, there is risk of development of adhesion between the anterior capsular rim and the posterior capsule.
Regardless of the relative position of Placozoans and sponges, the critical step of transformation to multicellulararity must have been accompanied by the development of adhesion molecules, extracellular matrix proteins (such as collagen), and cell-to-cell communication.
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To examine the factors influencing the development of adhesions after laparoscopic myomectomy (LM) and the efficacy of adhesion-preventing agents.
Recent studies have demonstrated that MMI-0100 reduces intimal hyperplasia in a mouse vein graft model, pulmonary fibrosis in a murine bleomycin-induced model and development of adhesions in conjunction with abdominal surgery.
Implants are usually serosal but can erode through subserosal layers and cause thickening and fibrosis of muscularis propria with development of adhesions, bowel strictures and gastrointestinal obstruction.
If the latter turns out to be the case it could impact NeoA's further development as a potential therapeutic agent given that the development of adhesion-independent anoikic resistance appears to be a functionally important phenotype that may contribute to metastatic tumor progression [36].
On stiff ECMs, cells develop the maximum allowable levels of adhesion, contractile force, and Rac activation (Fig. 4) such that even extreme values of ligand density can support migration (Fig. 5B,C), whereas soft ECMs yield slower development of adhesions and contractility (Fig. 4C,G).
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