Exact(1)
This NT-amino acid-specific feature permits the development of a tandem peptide ligation method employing three unprotected peptide segments containing different NT-amino acids to form consecutively two amide bonds, an Xaa-SPro (thiaproline) and then an Xaa-Cys.
Similar(59)
This study describes the development of a liquid chromatography-tandem mass spectrometry (LC MS/MS) based screening tool to simultaneously assess both the direct and the time-dependent inhibitory potential of xenobiotics on the seven major CYPs using a two-step approach.
In this paper, the development of the tandem reciprocating room-temperature active magnetic regenerative refrigerator and the numerical simulation for the effect of the dead volume are presented.
Prior approaches in development of Short Tandem Repeats (STR) markers were time consuming and inefficient.
Development of the tandem repeat coupled with endonuclease cleavage (TREC) method has greatly improved the efficiency of seamless gene deletions [ 21, 22].
For example, the development of short tandem repeat (STR or microsatellite) markers in non-model organisms is currently undergoing a complete paradigm shift in regards to the techniques and methods used to isolate potential markers, particularly for insects [ 5– 8].
For lipidomics, the development of electrospray tandem mass spectrometry and other tools has facilitated our understanding of the cellular lipidome, and we now believe that there are over 1000 members of the lipidome, opening up an entire array of new potential targets for therapeutic interventions.
Identification of PTM-modified peptides remains a challenging task in discovery proteomics despite significant progress made in the development of peptide tandem mass spectrometry during the last decade and emerging new software products with new concepts for prediction and detection of PTMs.
This feature was exploited for the development of an asymmetric three-component tandem reaction from imines, terminal alkynes, and sulfonylisocyanates in which a single gold(I) species can catalyze both the alkynylation of aryl aryl imines and the subsequent 5- exo-dig cyclization to afford enantioenriched five-membered carbamimidates.
Cyanobacteria had succeeded in the development of tandem operation of two photosystems (namely a high-potential water-oxidizing photosystem II and a low-potential ferredoxin reducing photosystem I) resulting in oxygenic photosynthesis [6].
This study describes the development of a tabu search algorithm for the design of tandem AGV systems.
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