Sentence examples for development of a systemic from inspiring English sources

Although there are various differences between these experimental models and the clinical setting, these reports support the hypothesis that certain current techniques and strategies of mechanical ventilation might contribute to the development of a systemic inflammatory response and multiple system organ failure.

Activation of the plasminogen system is tightly regulated, which is necessary to prevent the development of a systemic fibrinolytic state or tumor metastasis.

This is the development of a systemic culture of secrecy, evasion and misrepresentation.

This paper examines the development of a systemic multi-methodology for knowledge management in virtual enterprises.

This paper examines the circumstances and issues that contributed to a series of construction and engineering failures, to enable development of a systemic learning framework to contain and reduce design errors and potential failures and accidents.

Consistently, mounting evidence links the production of pro-inflammatory factors, by excess adipose tissue, to the development of a systemic chronic inflammatory state that contributes to the development of obesity-associated morbidities [1], [2], [3].

Such alterations lay the foundations for subsequent development of MOF, a systemic inflammatory process that leads to dysfunction of different vital organs and accounts for high mortality rates [ 9].

It has been shown that MERTK knockout mice have macrophages deficient in their ability to clear apoptotic cells, leading to the development of a progressive systemic lupus erythematosus-like phenotype [20], [32].

I/R injury can result in the development of a marked systemic inflammatory response and multiple organ dysfunction, leading to an approximate 30-40 % mortality rate [ 16, 17].

In support of the former, despite the development of a normal systemic immune response and equivalent parasite burden in the periphery, TIMP-1−/− mice have a significant decrease in parasite burden in the brain compared to WT controls.

However, unlike many chronic infectious agents, Mtb actually promotes the development of a robust, systemic immune response, which it subverts at the localized tissue-level to facilitate its prolonged survival, and, ultimately facilitate its transmission (Russell, 2007).