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In conclusion, we believe that several factors have had a role in the development of a severe ALTR in our patient.
Pereboom, I. T. et al. Development of a severe von Willebrand factor/ADAMTS13 dysbalance during orthotopic liver transplantation.
Sustained mechanical loading of skeletal muscle may result in the development of a severe type of pressure ulcer, referred to as deep tissue injury.
Continuous therapy with an angiotensin-converting enzyme (ACE) inhibitor has been shown to have a glomerular vasodepressor effect in the newly diabetic rat and to largely prevent the subsequent development of a severe, sclerosing glomerular injury.
This may have prevented the development of a severe form of coagulopathy.
Motheaten mice homozygous for the recessive mev mutation develop a fatal immunodeficiency syndrome associated with hypergammaglobulinemia, thymic aplasia, production of autoantibodies and development of a severe lupus like systemic autoimmune disease.
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This tropism could result in development of endocarditis, a severe and often lethal complication of Bartonella infection.
Furthermore, there have been recent reports of a shift in the balance of immune and neurotrophic mediators over the course of established BD, suggesting the development of a more severe dysregulation in the immune system and reduction in neurotrophic factors in patients with recurrent episodes of illness, poor remission, and a high burden of illness (Berk et al. 2011; Kauer-Sant'Anna et al. 2009).
This approach may be effective for the development of a consistent severe maternal morbidity surveillance system.
This is a protective factor against the development of a more severe outcome associated with ectopic pregnancy.
RF is a predicting factor for the development of a more severe disease course with the erosion of cartilage and bone [ 21].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com