Sentence examples for development of a semimechanistic model from inspiring English sources

The development of a semimechanistic model accentuates the ability to develop a predictive model for improved process operation.

Next we investigated the inflammatory response of the liver/immune MPS to stimulation with repeated doses of LPS using a semimechanistic model for production of two inflammatory cytokines.

A semimechanistic model including LPS-binding of TLR4, LPS-TLR4 complex internalization, TLR4 recycling, and TNF-α and IL-6 production by Kupffer cells was used to investigate possible mechanisms underlying these observations (Supplementary Figure 3).

The time course of sunitinib-related changes in ANC was described by a semimechanistic model for myelosuppression.

44 A model describing the non-small cell lung cancer response to gemcitabine treatment in humans used a semimechanistic model based on the principles of delayed response to treatment.

The current analyses aimed to establish a semimechanistic model that describes the systemic and ocular disposition of lampalizumab and CFD following ITV administration of single and multiple lampalizumab doses in patients with GA.

The analyses utilise a semimechanistic model proposed by Friberg et al (2002), describing the effect of cytotoxic drugs on bone marrow production.

Analyzing rich preclinical data with a semimechanistic model may be a relevant approach to facilitate the description of sparse clinical longitudinal tumor size data and to provide insights for the understanding of the drug mechanisms of action in patients.

A semimechanistic model was built to quantify the dynamic relationships between the kinetics of CTC counts and PSA concentrations during treatment in patients with mCRPC.

A semimechanistic model was successfully applied to describe sunitinib-induced myelosuppression.

To achieve this goal, a semimechanistic model was built, combining several advanced features in pharmacometrics.