This was similar to newer series of patients at 33% to 51% [ 37- 39], but lower than older series and a series from South Africa at 75%to95%5%.[ 2, 5, 35] The development of a higher proportion of subacute osteomyelitis and a lower proportion of long bone involvement could be linked to improved standards of living and hygiene.
HPV 16 predominates in penile LS and SCC and it is likely to be an aetiological agent in the development of a significant proportion of penile cancers.
Moreover, the VHL gene has also been implicated in the development of a significant proportion of sporadic clear cell kidney cancers (Gnarra et al, 1994).
These findings suggest that mutational alterations of the p53 gene are involved in the development of a significant proportion of some ovarian carcinomas (SCAs or EAs), especially in advanced stages.
The breast cancer susceptibility gene, BRCA1, is involved in the development of a significant proportion of familial breast and ovarian cancers and may also play a role in the development of sporadic breast cancer [ 1, 2].
Apocrine metaplasia is also commonly observed in breast cancers [ 26, 27] and may be responsible for the development of a substantial proportion of ER-negative disease in a potentially reversible manner.
By establishing that neural crest cells are involved in the development of a substantial proportion of olfactory sensory neurons, this work sets the stage for future studies of olfactory nerve growth and regeneration.
For these reasons, the development of an increasing proportion of vegetative GUs over time would lower the rate of increase in GU density over time.
Development of spinal curvature in the sagittal plane and maintenance of symmetry in the coronal and transverse planes are essential for correct balance control, which in turn is essential for the development of a properly proportioned locomotor system.
Peter Tatlor-Gooby athehe University of Kent points out that the UK spends less on research and development as a proportion of its national income than America, China and the EU (which includes, lest we forget, countries such as Slovenia and Bulgaria).
