Sentence examples for development of a profound from inspiring English sources

Given the numbers and diversity of drugs, chemicals and environmental agents; the various species in which they are studied and the time and dose factors that are critical to the induction of beneficial and adverse effects, it is only through the development of a profound knowledge base that toxicology and environmental health can rapidly advance.

Its main strength lies in the fact that, to orientate the European dimension towards education implies the development of a profound, structural Europeanist project, with schools and educational establishments at its heart, and the leadership of education professionals who are competent in the European dimension.

Adolescence is a unique window of development and a profound period of social, psychological, economic, and biological transition.

This state of development required a profound alteration in the genetic template to produce short pelvic blades, a forward-pointing big toe (adducted hallux), and other bipedal traits.

Long-term outcomes of WE can include development of a syndrome of profound memory impairment - Korsakoff syndrome (KS) - that appears to be related to additional disruption to diencephalic and hippocampal circuitry.

We have shown here that perturbation of the function of neuronal Rac GTPases during neuronal development has a profound effect on the development of a functional immune system.

The development of arbuscules requires a profound reprogramming of the root cell [ 16], and a wide number of genes which are specifically expressed in arbuscule containing cells have been identified [ 17, 18].

The study of sensory-motor development is experiencing a profound shift in scope, focus, methodology and theoretical foundations.

Johannes Fibiger, in full Johannes Andreas Grib Fibiger (born April 23 , 1867 Silkeborg, Den. died Jan . 30 , 1928Copenhagen) Danish pathologist who received the Nobel Prize for Physiology or Medicine in 1926 for achieving the first controlled induction of cancer in laboratory animals, a development of profound importance to cancer research.

Dysfunctional mitochondria are also known to have a profound impact on the development of a host of chronic and aging related conditions.

In the current cooperative interaction model, intraperitoneal coadministration of TGF-β2 and CTGF resulted in the development of profound abdominal fibrosis and disseminated fibrosis in extraperitoneal organs, thus indicating induction of a systemic fibrotic response.