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The recent development of a genome editing system using clustered regularly interspersed palindromic repeats (CRISPR) has made gene therapy for human diseases much more feasible.
In the near future, the development of a genome database for a variety of species will enable the analysis of intraspecies or interspecies genome-wide sequences.
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Two additional factors enabled accurate, sensitive and comprehensive transcriptional profiling of primate taste buds: rapid tissue collection resulting in minimal post-mortem RNA degradation, and the recent development of a genome-wide microarray specific for the macaque.
Here, we report the development of a genome-scale metabolic model of G. metallireducens and the application of the model to study its metabolism.
The development of a genome-wide linkage map is, therefore, essential to help shed light on the link between genotypic and phenotypic variation in such studies.
Development of a genome-wide set of markers polymorphic in elite germplasm would allow more cultivars and breeding clones to be genotyped and substantially advance potato breeding.
Development of a genome-scale resources for this group would augment the quality of research focusing on Hawaiian honeycreepers and facilitate comparative avian genomic research.
In addition, we report the development of a genome-wide data set of RT-PCR primers to streamline RT-PCR analyses.
libAnnotationSBML was used extensively in the development of a genome-scale model of yeast metabolism, the first model of this scale in which all compartments, metabolites, enzymes and complexes are unambiguously defined using MIRIAM-compliant annotations (Herrgård et al., 2008).
In this study, the development of a genome-scale metabolic model of C. thermocellum was used to provide a framework for analyzing the basic metabolic functions of C. thermocellum and improving its ethanol production capabilities.
Recently, several genome-wide studies have characterized the unique metabolic features of Geobacteraceae including the development of a genome-scale metabolic model of Geobacter sulfurreducens, the chemotaxis towards iron, and the synthesis of conductive pili [ 9- 13].
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