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The cumulative acquisition of these, but probably many more, genetic elements by E. faecium has resulted in the evolutionary development of a genetically distinct E. faecium subpopulation with a progressively increasing fitness in hospitalized patients (Willems et al. 2011).
The zygote represents the first stage in the development of a genetically unique organism.
In conclusion, disruption of the UL24 gene is a prime target for the development of a genetically attenuated live HSV-2 vaccine.
Here we describe the development of a genetically engineered Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) which expresses a modified form of juvenile hormone esterase (JHE).
One of the hallmarks of HIV infection is the rapid development of a genetically complex population (quasispecies) from an initially limited number of infectious particles.
Here, we describe the development of a genetically defined strain of l-lysine hyperproducing Corynebacterium glutamicum by systems metabolic engineering of the wild type.
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A critical step in the development of a genetically-encoded biosensor is the insertion of the tension sensor module into the POI; quite obviously, this involves the risk of altering the target protein's function.
On this basis, the development of Ad vectors with genetically incorporated antibody-derived moieties has been a long-standing goal.
However, a longstanding barrier to the development of Ad vectors with genetically incorporated scFvs has been the biosynthetic incompatibility between Ad capsid proteins and antibody-derived species.
According to Dow, the technology can knock one to two years off of the development time of a genetically modified crop a process that typically takes 10 years giving Dow a huge advantage.
In addition, this study provides a solid foundation for the development of a new genetically engineered vaccine.
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