Exact(4)
The role of the Process Engineer in the development of a candidate drug is to actively seek a robust and scaleable process through the application of experimental and theoretical process/chemical engineering science.
Consideration of binding competitiveness of a drug candidate against natural ligands and other drugs that bind to the same receptor site may facilitate the rational development of a candidate into a potent drug.
In the pharmaceutical industry, for example, the development of a candidate drug for a particular disease state will be the key priority.
After the initial study, 2 virus strains included in the panel (36 ) were selected for further development of a candidate IS for the WHO, and a candidate Japanese national standard (done in collaboration with the National Institute of Infectious Diseases in Tokyo).
Similar(56)
However, our work also highlights the need to explore new strategies to achieve high-level expression of these proteins for development of a vaccine candidate against Andes virus.
And, indeed, efforts to fast-track the development of a promising candidate vaccine could potentially help to bring this all to a swifter end, even if initially there were only enough doses to vaccinate health workers on the front line.
The study of such selective inhibitors will contribute to a better understanding of the CHIKV replication cycle and may represents a first step towards the development of a clinical candidate drug for the treatment of this disease.
Each aspect of drug bioavailability is key during the drug discovery process [3], therefore if adequate solutions to low bioavailability are not devised, further development of a drug candidate is unlikely.
These results constitute a good basis for the development of a new candidate reference material for selected pesticides in a cucumber matrix.
The DCM fraction of P. kurroa displayed potent anticancer activity and can be further explored for the development of a potential candidate for cancer therapy.
Raha and co-workers used it for the display of VP1 epitopes of enterovirus type 71 on live nonrecombinant L. lactis for the development of an oral candidate vaccine against hand-foot-and-mouth disease (Raha et al. 2005; Varma et al. 2013).
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