Exact(12)
Consistent with the widely accepted role of FGF8 during development, mouse nasal explants had high expression levels of endogenous FGF8 (Fig. 1, lane 2).
We show that, from the earliest morphologically recognisable stages of development, mouse skin papillomas induced by a chemical initiation-promotion regime are polyclonal.
Second, Shh, a key factor in limb development, exhibits a unique second phase of signaling late in development of the bat wing that is not present in the development mouse autopodia [ 9].
During early development, mouse mammary glands, like other epidermal appendages, first appear as thickenings of the ectoderm, which then expand to form solid buds of epithelial cells protruding into the mesenchyme.
The TRIM32 gene is suggested to be involved in muscle and nervous system development mouse phenotypes (Kudryashova et al. 2009) and deletions in this gene are also reported in cases with attention deficit hyperactivity disorder (Lionel et al. 2011).
In meningeal cell development, mouse Zic proteins are present in the primitive meninx (meningeal cell precursors), and a deficiency of Zic2 or Zic1/Zic3 results in impaired proliferation and differentiation of meningeal precursors [ 4].
Similar(48)
In therapeutic antibody discovery and early development, mice and cynomolgus monkey are used as animal models to assess toxicity, efficacy and other properties of candidate molecules.
After tumor development, mice were castrated.
Bone morphogenetic protein receptor type 2 (BMPR2) is essential for development; mice lacking the gene fail to progress to gastrulation [ 1].
To study lesion development, mice were decapitated 24 h after NMDA injection under deep anesthesia with 100 mg/kg pentobarbital.
At the end of the monitoring of CIA development, mice were sacrificed and lymph node cells were collected for proliferative analysis in response to CII.
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