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To elucidate the interplay between the four E3 ubiquitin ligases and the Notch ligands in mammalian development, more comprehensive genetic studies of these four E3 ubiquitin ligases are required in a single organism.
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In a later study, taking advantage of recent technological developments, more comprehensive sets of inflammatory mediators were analyzed in serum and saliva obtained from NOD mice [ 56].
Understanding how project leaders struggle with and overcome these challenges will help facilitate the development of better supportive structures for disease management projects, as well as the development of more comprehensive project plans and budgets.
Wagner and colleagues [ 2] developed the Chronic Care Model (CCM) as a framework for the development of more comprehensive and integrated chronic care.
This will enable the development of more comprehensive decision support tools for assessing future energy scenarios, integrating main policy concerns when assessing renewable energy options.
The goal of delivering more consumer-centered research models will be supported by the development of more comprehensive outcome assessments for BD.
This study has demonstrated that broad metrics have been applied in LMICs, however identified the need for the development of more comprehensive measures that are locally applicable.
We need to take advantage of these new technologies to allow the development of more comprehensive and more cost-effective diagnostic testing.
The accompanying economic analysis for PGx-driven treatment optimization has to take into consideration all medications that may differ from patient to patient, necessitating the development of more comprehensive and flexible models.
The approach used in this work allows the selection of epitopes with potential to induce cross-reactive immune responses, providing useful tools for studies in autoimmunity and to the development of more comprehensive vaccines.
Finally, this understanding could also lead to the development of more comprehensive legislation and policies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com