Although many studies have demonstrated the essential role of Meis1 protein in retinal development, its downstream target genes and detailed mechanisms of how it functions in RPCs and retinal development remain largely uncharacterized.
However, the RRS was incompatible with sustainable rural development of its target region because it has resulted in significant negative unintended impacts, most notably excess housing output, which in turn has contributed to high vacancy rates.
Regulation of the actin cytoskeleton and MAPK signaling pathway are among the identified lung development-specific non-coherent ontological target sets for miR-140, which is significant in lung development for its target non-coherence (Table S4).
Notch signalling plays an important role in endocrine development, through its target gene Hes1.
Role of YODA a MAPKKK from Arabidopsis was characterized in stomatal development with its targeting downstream MAPKKs.
The up-regulation in J compared with A was confirmed for mdm-miR156 during leaf development, while its targets, SPL2 and SPL9, showed higher expression levels in A than in J from March to August, with their levels gradually increasing.
South Africa aimed to spend 45 billion Rands on research and development and reach its target for gross expenditure on research and development of 1.5% of GDP by 2014.
Before he slides behind the wheel, however, Mr. Parry-Jones pores over piles of statistical information that shows how each car and truck under development is meeting its targets for driving performance, targets that are as stringent for a Jaguar as they are for a Focus, but specific to the brand the vehicle represents.
In addition to its essential role in melanocyte development, expression of Mitf and its target genes is seen in many melanoma cells [21], [22].
Here, we took advantage of a unique hypomorphic Mdm2 allele (Mdm2puro) to examine the contribution of this ubiquitin ligase to cerebellar development in the presence of its target, wild-type p53 [38].
