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TGF-β signaling, required for physiologic lung development, is activated in the vascular and airway smooth muscle and the alveolar and airway epithelium throughout late lung development [20].
The process begins today when Eddie Jones practices at 100% for the first time since suffering a sprained right shoulder Feb. 19, then gains momentum as Jones, barring an unforeseen development, is activated in time for Sunday's game against Houston.
For instance, the hedgehog pathway, one of the fundamental signal transduction pathways in animal development, is activated only if the signalling domain is cleaved off from the autoproteolytic domain of hedgehog (Lee et al, 1994).
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This finding indicates that protective mechanisms against complication development are activated early and chronically in the course of the disease.
These observations support the fact that numerous genes that are important in development are activated in the early stages and they are gradually repressed in the more advanced stages, up to the L1 stage.
To address this, sorted CD62LhiCD44lo (naïve) and CD62LloCD44hi (effector) CD4+ T cells from Stat5−/− and Stat5+/+ mice during EAE development were activated by anti-CD3 plus anti-CD28 in the presence or absence of IL-7, followed by GM-CSF expression examination.
During embryonic development, HIF1α is activated in the growing placenta [8].
For example, the transpositional activity of TEs in plants is relatively silent during normal development but is activated by stresses, such as wounding, pathogen attack, and cell culture [ 4].
NFATC3 is a transcription factor involved in T-cell development that is activated by hypoxia (Cante-Barrett et al. 2007).
During development STATc is activated by DIF, which induces the differentiation of prestalk O cells [ 17, 48].
While during normal development STAT5 is activated primarily by PRL signaling pathways, EGF and GH signaling pathways can also contribute [ 32, 70].
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