La Manno, G. et al. Molecular diversity of midbrain development in mouse, human, and stem cells.
The LIM homeodomain transcription factor, LHX3, is essential for pituitary development in mouse and man.
Thus, Dkk1 expression appears to be required in the definitive anterior mesendoderm for early anterior development in mouse (Mukhopadhyay et al., 2001).
The Allen Institute for Brain Science was created in 2003 to produce standardized, systematic surveys of gene expression across development in mouse, macaque, and human brains.
Vascular endothelial growth factor C (VEGF-C), the major effector of lymphangiogenesis, is indispensable for lymphatic development in mouse embryos and essential for most lymphangiogenic processes in adults1,2,3.
In the first study, Harvard University developmental biologists Cliff Tabin, Patrick Tschopp, and colleagues traced penis development in mouse, lizard, chick, and snake embryos.
Our results indicate that CD177 is dispensable for normal neutrophil development in mouse bone marrow or distribution within secondary lymphoid tissues, which agrees with the observation that up to 5% of individuals have normal neutrophil counts and function with no detectable CD177 expression (Matsuo et al., 2000).
So far, our knowledge of initial steps in tumor development in mouse models of prostate cancer is limited.
Study of tumor development in mouse prostate cancer models can be instrumental in understanding human prostate cancer.
Here we present the analysis of the requirement for ATF2 in CNS development in mouse embryos, specifically in the brainstem.
In tumor biology, interferon γ is the master regulator of the Th1 response and enhances tumor immunogenicity and abrogated tumor development in mouse models [22].
