The introduction of the polymerase chain reaction (PCR) [ 2] method in the 1980s resulted in the development of a multitude of diagnostic tools that helped improve the efficiency of diagnostics and the characterization of infectious-disease agents by detecting and identifying their DNA.
On the background of an increasing interest in participatory approaches in urban development, a multitude of participation methods has been created and tested over the past years.
The Esrp KO mice reveal the essential role of the Esrps in maintaining an epithelial cell-specific splicing program for normal development during mouse embryogenesis, underscoring the role of AS in the development of a multitude of organs and appendages, and the requirement of the Esrps in critical epithelial cell functions.
: Medication-induced sleep disturbances are a major concern in drug development as a multitude of prescription drugs alter sleep patterns, often negatively.
The role of smoking in the development of a multitude of chronic diseases such as coronary vascular diseases (CVD) [ 3, 4] and various neoplasm [ 5, 6] has been substantially studied.
The growing interest in the endothelium as a central player in numerous diseases has stimulated the development of a multitude of new circulating markers and in vivo evaluation techniques [ 1].
The success of rituximab and the identification of other CLL lymphocyte surface antigens have spurred the development of a multitude of monoclonal antibodies targeting distinct proteins and epitopes in an attempt to target CLL cells more effectively.
The development of a multitude of divergent sets of priority areas, often competing rather than complementary, is problematic because it creates redundancies in planning and conservation action by different organizations and distracts from a "commonly adopted blueprint for action" [12].
Here, we chronicle the development of a multitude of site-specific conjugation strategies for assembly of ADCs and provide a comprehensive account of key advances and their roots in the fields of bioorthogonal chemistry and protein engineering.
Moreover, during the development of many diseases and in a multitude of pathological states, EMVs prepared from patients were found to harbor specific miRNAs that were detected at lower levels or not at all in EMVs from normal healthy subjects.
