Nevertheless, the data collected on the effects of BHT on mouse lung tumor development have broadened the concept of two-stage carcinogenesis and complement the evidence for initiation- promotion available for other epithelial tissues such as liver, colon, stomach, trachea, urinary bladder and mammary gland.
Describing the patterns of gene expression during embryonic development has broadened our understanding of the processes and patterns that define morphogenesis.
Rapid development of zinc biology has broadened the applications of Zn-incorporated biomaterials to tissue engineering but also raised concerns about the long-term safety of released Zn2+ ions.
Development of the Griggs technique has broadened the indications for tracheostomy to include emergency settings [ 23], whereas the translaryngeal technique is contraindicated.
The development of the self-piercing riveting (SPR) technology in recent years has broadened the application of the technology in the automobile industry.
The development of multiple new agents for the treatment of type 2 diabetes has broadened the options for patient-specific therapy.
Utilization of effective bioinformatics tools has broadened the applications of EST analysis into the fields of genomics, marker development and genome annotation among others [ 2- 4].
But the effort has broadened, the scientists say.
Moreover, developments in commerce and technology have broadened the scope of white-collar crime to include cybercrime (computer crime), health-care fraud, and intellectual property crimes, in addition to more-traditional crimes involving embezzlement, bribery, conspiracy, obstruction of justice, perjury, money laundering, antitrust violations, tax crimes, and regulatory violations.
