Two alternative specifications were tested in the New Hampshire and Oregon analyses: indicators for counties where wind power development had been halted in the face of active opposition and indicators treating each county individually.
However, to date, clinical developments have been halted because of psychiatric side effects.
Although further clinical development of tanespimycin has been halted, other hsp90 inhibitors, including retaspimycin (IPI-504; Infinity Pharmaceuticals, Cambridge, MA, USA) and AUY922 (Novartis, Cambridge, MA, USA) are currently under evaluation in early-phase clinical trials as single agents or in combination with trastuzumab (NCT00817362, NCT00526045 and NCT01271920).
Development on TapIn.TV, meanwhile, has been halted.
The development of CDP-571 has been halted.
102 Further development of this agent has been halted while the manufacturer, NeuroSearch (Ballerup, Denmark), seeks a partner to continue commercialization.
Results from recently completed multicentre trials indicate that coformulated AS+CD can cause serious haemolysis in children who are G6PD deficient so further development of this drug combination has been halted.
The development of previous dual PPAR agonists has been halted by safety concerns; however, the safety profile of aleglitazar is encouraging [ 36].
The PI3K/Akt pathway is an important regulator of many key physiologic processes and the development of several classes of Akt inhibitors has been halted because of toxicity [19], [20].
Dealing with the complexity of multiple genomes comparisons has been halted by the unparalleled development of appropriate software tools.
