Moreover, since miRNAs were previously demonstrated to affect embryonic development [ 8, 17], we selected some miRNAs related to embryonic development for further analysis.
It is noted that the stringent selection criteria imposed in this study for differential expression would preclude certain genes, although present in the SAGE datasets and relevant to cancer development, from further analysis (see example below).
In support of this, CycC-CTAP protein levels were observed to decrease throughout development and further analysis suggested that the decrease was promoted by high levels of extracellular cAMP which mimics conditions found at the mound stage of the life cycle.
Therefore, we selected only the largest pathway, neuron development, for further analysis.
Normalized bead summary intensities were imported in BRB-ArrayTools (developed by Dr. Richard Simon and BRB-ArrayTools Development Team) for further analysis.
Clearly, the mechanisms by which O-GlcNAc modifications regulate neuronal development will require further analysis.
The clones we did obtain showed ectopic branching defects, but also severe axon targeting phenotypes, suggesting that the EGFR is required early in DCN development and precluding further analysis of these clones.
To minimize the influence of drug therapy on the development of NAFLD, a further analysis adjusted for anti-hyperlipidemia and diabetic mellitus drugs was performed.
The mean mental development index or predicted mental development index was used for further analysis: overall mean scores 89 (SD 19).
The individual contribution of these mechanisms to the development of TB, however, awaits further analysis.
