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By contrast, in the anopheline-mediated system in which the L3 development function was of a facilitation form, a subcritical bifurcation was observed in which a discontinuous jump in the Mf prevalence at the TBR occurs regardless of whether the worm mating function is included or not (Fig. 2C,D).
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Nine genes, ADAMTS1, THBS1, TIMP3, PTGS1, NCKAP1, EVI1, MFGE8, ITGA2, ENST00000353442, with embryonic development function were upregulated in engrafted cells.
Interestingly, nine genes (ADAMTS1, THBS1, TIMP3, PTGS1, NCKAP1, EVI1, MFGE8, ITGA2, ENST00000353442, p = 2.62E-04 - 3.80E-02) with "embryonic development function" were also upregulated in G0 cells of BM and MPB but relatively unchanged in G0 and G1 of UCB (Table 2).
For physiological system development and function, behavior, hair and skin development and nervous system development function were among the top.
The top 'Physiological System Development and Function' was 'Connective Tissue Development and Function' with seven enriching genes (CYR61, IQGAP1, NF2, KRT8, ALDH1A3, MXD1, and CYP27B1).
Consistent with a recent report, T cell development and function was found to be normal in PTPN4-deficient mice [23].
A network involving 35 genes attributed to neural development and function was identified using Ingenuity pathway analysis, emphasizing EGFR as the most outstanding interaction partner in the network.
For the pool of DE genes, embryonic development and tissue development, hematological system development and function, cell-mediated immune response, and nervous system development and function were listed at the top of physiological system development and function.
Hematological system development and function, immune cell trafficking, and nervous system development and function were most overrepresented in physiological systems development and function.
In addition to eye development, Rx function is required for the normal development of the ventral forebrain [14].
11 The association between development and cognitive function was investigated with regression models.
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