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We discuss how these insights have either allowed confirming the choices made, and thus proceed with development efficiently, or led to design ideas to improve the application.
In the absence of IL-6 and TGF-β, neither the ROR nuclear receptors nor IκBζ induced Th17 development efficiently.
However, high drug concentrations are required to antagonize tumor development efficiently and often several chemotherapeutics need to be combined to circumvent possible drug resistance of cancer cells [ 3].
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Finally, many open-source companies find they can also run research and development more efficiently, and save R&D dollars, because a broad community of users is continually iterating and improving on open-source products.
Thus, the FcOBHS HDACi conjugates represent a novel approach to the development of efficiently dual-acting agents for treatment of breast cancer.
Furthermore, based on analysis of recent ERP software projects, this work presents a feasible estimation model to satisfactorily estimate the person-hour of an ERP system development project efficiently.
Given the lack of fundamental knowledge about the causes and pathophysiology of depression, it is a challenge for Phase I in antidepressant development to efficiently and thoroughly test new drugs.
Increasing knowledge of such degradation mechanisms may enable improvement of tyrosine kinase inhibitors or the design of "smart" treatment combinations, as well as novel drug development to efficiently enhance erbB2 downregulation in cells.
In the present study, histological evidence showed concomitant anti-inflammatory activity in the lungs of SPM-treated mice in accordance with Figures 6, 7 and 8. Whole-lung HE images in mice with/without primary tumor resection indicated that SPM could control metastasis development more efficiently than free DTX.
The 20,000 or so NGOs there operate mainly in the country's 86,000 villages, providing education, health, small loans and agricultural development far more efficiently than the corrupt and inefficient government.
For both ILC and cNK cell development, Nfil3 can efficiently activate Id2 expression, probably explained by its direct binding to the Id2 locus (Xu et al., 2015).
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CEO of Professional Science Editing for Scientists @ prosciediting.com