Sentence examples for development discontinuation from inspiring English sources

This occurs either because of lack of public data on the reasons behind development discontinuation, or because a combination of different elements often play a role in the demise of a particular drug candidate, making it difficult to identify specific contributing factors.

Stopping antidepressants abruptly has been shown in many cases to be associated with the development of discontinuation symptoms.

Our framework also allows different stakeholders to specify different thresholds for decision-making, depending on their perspective and particular needs (e.g., for exploration, further development or discontinuation, regulation, clinical uptake, insurance coverage, dissemination, practice guideline development, or marketing).

On March 22 , 2011 Oracle announced discontinuation of development on Itanium, although its technical support for its existing products would continue.

The development of rash necessitated discontinuation of TVR in 6% and of the entire regimen in 1% of the cases.

The most common causes of study discontinuation were development of exclusion criteria (3.8%) and protocol violations (2.9%).

Despite the discontinuation of internal game development at 3D Realms, development of the game did not cease entirely.

He said the discontinuation of Flurizan development would allow investors to focus on the company's fast-growing genetic testing business.

Although armodafinil was generally well tolerated in this and prior phase 3 studies, the lack of statistically significant efficacy on the primary outcome in two of three studies has led to the discontinuation of the development program for adjunctive armodafinil in bipolar I depression.

However, American College of Rheumatology 50%ACR5050) improved benefits were less impressive, which probably led to the discontinuation of clinical development activities [ 5].

However, accrual was terminated on 7 April 2012, after completion of three dose levels (DLs), due to discontinuation of RO4929097 development.