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The influence is manifested by microstructural development, defect formation and metallurgy transformation in the weld region.
In addition to the defects described above, we observed a lung development defect.
Accordingly, c-fos gene knockout mice exhibit a severe bone development defect, osteopetrosis [29], [30], due to a defect in osteoclast differentiation [31].
The effect of Cbl inactivation in rescuing the development defect in Vav1-/ thymocytes might result from the effects identified above, through activation of events that are normally mediated by Vav1.
Our finding that mutation of K220 results in a significantly less active kinase is important with regard to the interpretation of a recent genetic study in which knock-in of the K220M mutant resulted in a dramatic kidney development defect [45] likely due, at least in part, to defects in renal branching morphogenesis [57].
We found that the xprG1 mutation partially suppresses the conidiophore development defect in the fluG701 mutants.
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Our RT-PCR data confirm earlier published data indicating that β-amylase expression is linked to starchy endosperm development, but α-amylase is not expressed on late seed development stages [ 14], moreover over-expression of α-amylase in developing seed leads to development defects [ 15].
Is resin infiltration an effective esthetic treatment for enamel development defects and white spot lesions?
As reported before, we found that deleting Cdc42 in embryonic cardiomyocytes caused lethality with heart development defects (thin ventricle walls).
This plasticity, however, poses a risk for misregulation and may underlie a number of hereditary disorders, development defects, and cancer.
More than 49 syndromes have been associated with one or more missing teeth [3, 6]; the main ones are hypohidrotic ectodermal dysplasia, incontinentia pigmenti, Down syndrome, craniofacial dysostosis, and syndromes associated with growth and development defects [2, 11].
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