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The design of computational models is path-dependent: the choices made in each step during model development constrain the choices that are available in the subsequent steps.
The discovery that the rapid cell cycles of early development constrain the length of genes expressed during this period can be embedded in the larger context by noting that short genes also tend to be evolutionarily young [ 7, 52, 71].
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To forecast the housing floorspace distribution, a three-step Floorspace Development Model (FDM) is developed in this study based on indicators of permissible development constrains, floorspace areas, and house rents.
What we have just witnessed is delegates from 192 countries talking about making sacrifices, slowing their development, constraining their industry, taxing their citizens, in a collective bid to stifle climate change.
Whether or not India's Prime Minister, Narendra Modi, will agree to have his country's vital development constrained by a legally binding emissions treaty remains to be seen; it looks very doubtful.
Development constrains the evolution of biological traits in multiple ways, and behavior especially, since behavior depends on development at both neurological and psychological levels.
Iran's educated population, high human development, constrained economy and insufficient foreign and domestic investment prompted an increasing number of Iranians to seek overseas employment, resulting in a significant "brain drain".
Correspondingly, we also found that high light triggers endophyte pathogenicity, while low light favors endosymbiotic development, constraining recruitment of endophyte-infested seedlings to shaded understory by reducing seedling survival in direct light.
We found that high light triggers pathogenicity of the fungus, while low light favors endosymbiotic development, constraining recruitment of endophyte-infested seedlings to the shaded understory by limiting survival of seedlings in direct light, i.e., constraining the niche-space filling [4] of the otherwise highly successful I. deltoidea.
However, despite significant gains in systems development, constrained access to primary health services and quality of care remains as a challenge.
Recently, Roux and Robinson-Rechavi (2008) have used zebrafish microarray and mouse expressed sequence tag (EST) data spanning, respectively, 14 and 26 developmental stages to investigate whether the timing of expression during development constrains genes' "evolvability".
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