Sentence examples for development compounds from inspiring English sources

This is due to the routine testing of development compounds in albumin binding assays.

From measured physical and in vitro properties, it is also possible to predict pharmacokinetic and pharmacodynamic data to estimate the dose of development compounds.

It has been reported that the solid form of active pharmaceutical ingredients (APIs) has significantly impacted quality and consistency of the final dosage form for drug development compounds (Newman and Byrn 2003), especially for solid oral dosage formulations.

In 1997 Lipinski published a key paper identifying molecular features that appear to be found in orally available drugs [11] the Lipinski "rule of five" has since become the yardstick by which potential development compounds are judged.

Technology developers are beginning to realize that direct, early dialogue on the evidence requirements of the major pricing and reimbursement agencies, before phase 3 clinical trial designs for their key development compounds have been finalized, may be beneficial.

However, only a few laboratories have investigated whether in vitro systems can be used in the toxicogenomics evaluation of development compounds.

DPC 961 (Fig. 6) was a development compound indicated for the treatment of HIV infections and was developed as a neutral molecule (Staszewski et al. 1999).

The prayer center in Seynod, situated on a housing development compound and opened in 1980, was renovated three months ago.

Similar ratios can also be detected in the Prous Drugs of the Future subset as an independent development compound source i.e. with a 75% overlap with GVKBIO papers but 37% for patents.

The SAscore cannot compete with more sophisticated approaches for estimation of synthetic accessibility which reconstruct the full synthetic path, in cases when the results are critical, for example when making decision about selection of a development compound from several candidates.

He credited Polytron's long development cycle to his own inexperience in game development (compounded by the team's small size and difficulty in setting reasonable milestones), the game's scope, and Fish's perfectionism.