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Symptoms vary and may include delayed growth and development, asymmetry of the face, hypotonia, and intellectual disability [ 39- 41].
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Pathogenetic mechanism of spinal deformity development is a growth asymmetry underlaid by disorders in chondroblast proliferation and differentiation and in structural organization of the growth plate, as well as changes in the proteoglycan spectrum.
Trauma and infection in the condylar region may also result in the development of asymmetry and perhaps ankylosis of the temporomandibular joint leading to a secondary functional impairment.
By measuring how well an organism can cope with genomic stress and environmental perturbations, symmetry may be an honest signal of gene-quality given that studies show that such stressors during development increase asymmetry [48].
The failure of our study to find robust differences in other regions than the planum temporale may also relate to the possibility that some structural asymmetries may parallel the ontogenetic development of functional asymmetries (experience-dependent plasticity; Josse et al., 2009), and hence might be more difficult to detect in childhood than adulthood.
The results showed that incubating the animals in a GM-solution had no effect on otolith growth, but the development of otolith asymmetry was affected.
The 5200 and 7200 cm−1 bands broaden significantly with increasing temperature with the broadening of the 7200 cm−1 including development of an asymmetry toward higher frequency at the highest temperatures.
RME is considered the treatment of choice for functional crossbite because it eliminates the lateral functional mandibular shift, preventing the development of skeletal asymmetry and of muscle function disturbances [56, 59].
And Legrell PE and Isberg A also demonstrated a development of mandibular asymmetry from the condyle-disc complex disorder after surgically altering unilateral TMJ disc in animal study [22].
These results suggest that CYC-like genes are also involved in the development of floral asymmetry and the determination of adaxial identity of floral organs in the monocotyledon Alstroemeria.
These results indicate that regional cell shape changes control the development of anteroposterior asymmetry in KV, which is necessary to generate coordinated asymmetric fluid flow and left right patterning of the embryo.
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