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Design changes are unavoidable in new mechanical product development, and the propagation of changes imposes negative impacts on the design cycle and cost.
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The effect of different material, geometric and loading parameters on the damage development and propagation, and the energy absorbed in each one of the four failure modes have been examined.
Cross-sectional views of the reservoir (illustrating oil saturation distribution) at different stages throughout the 20-year simulation time are shown in Figs. 6, 7, 8, 9, and also, the figures show the development and propagation of the solvent vapour chamber, which have been predicted by running the simulation model, during the time of the operation.
Three scales of fracture corresponding to different phases of the development and propagation of the crack are identified, including microfracture at the particle matrix interface and mesofracture limited to the matrix surrounding the particle.
High levels of saturated NEFA, such as palmitate, when combined with hyperinsulinemia, may activate human monocytes to produce proinflammatory cytokines and support the development and propagation of the subacute, chronic inflammatory state that is characteristic of insulin resistance.
In addition, central obesity is associated with increased levels of saturated nonesterified fatty acids, which in combination with hyperinsulinemia, may activate human monocytes to produce proinflammatory cytokines and support the development and propagation of the subacute, chronic inflammatory state [ 41].
The increased understanding of the mechanisms promoting vascular damage has recently led to a sharper focus on proinflammatory pathways, which appear to play a key role in the development and propagation of the disease.
It appears therefore that a misunderstanding of the scope of the claims of these earlier studies together with the known role for gene duplication in the diversification of snake venom (Kordiš and Gubenšek 2000) is responsible for the development and propagation of the attractive, but ultimately unsupported, duplication and venom gland recruitment hypothesis.
In Part 1 the development and early propagation of cracks is considered in terms of the basic damage mechanisms and the relative size of the crack with respect to applicable microstructural feature(s).
These findings demonstrate the potential for 'phases' of pathway development and propagation within the buffer, resulting in successive migration episodes over the repository lifetime.
The surface layers contract against the inner layers, leading to the development of tensile stress and the propagation of cracks.
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