Developmental biologist (1927-2007) An expert in embryonic development and a pioneer of in vitro fertilisation research, in the mid-1950s McLandn and colleagues successfully fertilised mouse embryos outside the womb, coaxed them to an early stage in embryonic development, and then implanted them in surrogates.
Originally described as crucial transcriptional components during development and differentiation, pioneer factors have recently been implicated as mediators of nuclear receptor function under both normal and pathologic conditions [24].
Not only for this reason but also because of their key role in early development and cancer, pioneer transcription factors as well as HMG proteins are the next two groups likely to open new therapeutic windows [ 21, 32].
In the 50 years since it was undertaken, the Snowy Mountains scheme has been regarded as a proud symbol of Australia's development, and of the pioneering spirit of its people in turning hostile elements to their advantage.
This is because fleshy-fruited species are able, thanks to artificial perching sites, to appear earlier than they would under natural conditions, in which these species follow the expansion and development of pioneer anemochorous species acting as natural perching sites.
It is a highly innovative field investing heavily in research and development, pioneering new technologies and concepts, and furthering performance and comfort.
Seoul Semiconductor, which has pioneered development and manufacturing of next-generation LED light sources since 1992, notes that Acriche outlasts incandescent and compact fluorescent (CFL) bulbs, and due to its long life is less costly to use than traditional lighting methods.
Tibor Kalman, who, at twenty-eight, is Barnes & Noble's director of planning and development, is pioneering a games department and a New York, N.Y., Boutique at the branch.
BUG is now a part of the growing OMAP community supporting open development, and TI has been a pioneer in open source hardware".
Liu and Jordan developed the following model[35] and pioneered the development of correlations for the empirical estimation of the beam and sky-diffuse components of insolation[59].
