Sentence examples for development and peripheral from inspiring English sources

In addition, neither B7-1 nor B7-2 expression alone is sufficient for the development and peripheral homeostasis of Tregs.

In this study, therefore, we investigated the relative contributions of B7-1 and B7-2, the only known ligands of CD28, on the thymic development and peripheral homeostasis of Tregs.

AMPK was found to mediate a subset of LKB1 functions in T lymphocytes, as mice lacking the α1 subunit of AMPK displayed similar defects in T cell activation, metabolism, and inflammatory cytokine production, but normal T cell development and peripheral T cell homeostasis.

IL-2 signaling appears to be required for both the thymic development and peripheral expansion/maintenance of Tregs [31], [32], [33].

We did not find any evidence for this, as Lmna-/ bone marrow completely reconstituted wild-type recipient mice with normal T and B cell development and peripheral lymphocyte populations for more than 40 weeks following bone marrow transfer.

Our previous work has shown that the thymic microenvironmental defects in the Foxn1Δ/Δ mouse result in a variety of secondary effects on thymocyte development and peripheral T cell function [10], [20], [21].

Among these genes, 96 genes were associated with nervous system-related terms and specifically with nervous system development, central and peripheral nervous system development, brain development, neurogenesis, generation of neurons, neuron differentiation and axonogenesis (Table 1 and supplementary Fig S4).

The neuropeptide galanin is present at high levels within the dorsal root ganglia (DRG) and spinal cord during development and after peripheral nerve damage in the adult.

Here, we took advantage of this Cre recombinase distribution pattern to ascertain the transition effect between the central area with regular development and more peripheral parts with developmental apoptosis within the same retinal slice (Fig. 6).

It seems that tasiRNA-ARF regulation represses central floral organ development and enhances peripheral floral development under drought stress.

A subset of these cells is referred to as DCs; whether there is a genuine functional distinction between DCs and other MPS cells in terms of antigen-presenting activity has been debated elsewhere.5 Cells of the MPS may also act as powerful suppressors of T-cell activation and probably have a major function in the development of central and peripheral tolerance.