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Widely observed dysregulation of microRNAs (miRNAs) in human cancer has led to substantial speculation regarding possible functions of these short, non-coding RNAs in cancer development and manipulation of miRNA expression to treat cancer.
Among the DFG-funded projects is the University of Würzburg's Sonderforschungsbereich "Development and Manipulation of Pluripotent Cells".
Qualitative analysis of data is characterized by the development and manipulation of concepts [ 21].
The introduction of non-natural entities into proteins by chemical modification has numerous applications in fundamental biological science and for the development and manipulation of peptide and protein therapeutics.
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An improved understanding of how tumours evade T-cell surveillance, coupled with technical developments allowing the culture and manipulation of T cells, has driven the exploration of therapeutic strategies based on the adoptive transfer of tumour-specific T cells.
Despite this growing interest in the development of biotechnological processes in other yeast species, the development of tools for the investigation and manipulation of these organisms still lags behind the advances in S. cerevisiae for which the broadest spectrum of methods for the engineering of production strains and the best knowledge about manipulation and cultivation are available.
But reflecting the state-of-the-art of the tools available for implementing the principle of community involvement to its full extent, it is also recognized that there is a need for better tools for collaborative ontology development and for manipulation of ontologies in general (Buffa et al. 2008).
Bioinstrumentation is the development of technologies for the measurement and manipulation of parameters within biological systems, focusing on the application of engineering tools for scientific discovery and for the diagnosis and treatment of disease.
Contemporary biomedical research requires development of novel techniques for sorting and manipulation of cells within the framework of a microfluidic chip.
NIGMS: Development of novel methods for mutagenesis and manipulation of gene expression.
In parallel with virtual screening methods, concomitant developments in cheminformatics including identification, design and manipulation of drug-like small molecule libraries have been achieved.
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