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As a result, they "cracked open the opaque process" of drug development, altered the patient-doctor relationship and "changed the whole face of advocacy," he said.
Altering visual experience early in development altered the statistics of tectal activity, and dark rearing also caused a long-lasting deficit in the ability to capture prey.
Considering the role of the circadian system in the control of cell division [8] [10], especially important during early development, altered clock mechanisms might lead to multiple subtle embryonic abnormalities.
These include embryo and emerging leaf symmetry anomalies, leaf shape defects, premature inflorescence development, altered phyllotaxy, reduced petal size, abnormal stamens, sterility, and root growth defects [ 49].
To show time-dependent information flow in embryonic development altered by 1α,25(OH)2D3 treatment, GO networks of enriched GO-GO interactions were reconstructed.
Tet1 deficiency is associated with defects in neural development, altered expression of neuronal transcripts, and deficiencies in spatial learning and memory.
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Previous studies have demonstrated that alterations to DA homeostasis during development alter the expression of GABAergic interneurons.
Compromises in biodiversity and biotic integrity from human development alter native wildlife communities.
Lesions of the cholinergic system during development alter cortical circuitry [42], [43] and neuronal morphology [44], [45], with implications for attention.
The effects of these endocrine disruptors extend beyond embryonic development, altering sex-steroid physiology in exposed animals.
Steroids play important roles in foetal brain development, altering neuronal migration, synaptic plasticity and neurotransmitter activity [10].
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