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Ideally the mutant population must produce a mutation frequency that is conducive to high-throughput screening but is below a threshold that causes extensive sterility and plant development alteration.
This segmental aneuploid carries three copies for most of the short arm of chromosome 5 and displays a phenotypic syndrome that includes leaf development alteration, delayed flowering and floral morphology changes.
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The treatment with lamotrigine during breastfeeding is safe and no serious adverse effects or cognitive and development alterations have been reported [86].
The Albert Park conservation area, covering much of West Didsbury, places planning restrictions on development, alterations to buildings, and pruning of trees.
Mutations in LHP1 cause changes in inflorescence development, alterations in leaf morphogenesis and cell size, and affect flowering time [26] [29].
During development, alterations in the ratio of neurons to glia may severely perturb neuronal function.
Problems associated with TMJ ankylosis in a child include issues with airway maintenance, feeding difficulties and speech development alterations.
Upon exposure to dichlorvos, worms show a time-dependent response with progressive delays in development, alterations in metabolism, increased cellular repair, and alterations in innate immunity functions.
We show for the first time that muscle tissue suffers metabolic alterations early in the course of disease development, alterations that influence the course of the pathology.
Of all indicators of disrupted sexual development, alterations in retained nipples were the most sensitive end point, with effects becoming noticeable at the lowest doses.
Therefore, by contributing to the hematopoietic clone development, alterations of stromal cells within hematopoietic stem cell niches are key actors of PMF pathogenesis process illustrating the "Bad Seeds in Bad Soil" concept that we proposed.
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