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The H5N1 avian influenza virus has been periodically jumping from birds to people and causing sporadic deaths for 16 years without developing sustained transmissibility among people.
Pentoxifylline is a water-soluble model drug with a short half-life, consequently developing sustained release preparations would be beneficial.
In subjects developing sustained atrial or ventricular arrhythmias, the study drug is discontinued and the event is reported as an adverse event.
The rationale behind developing sustained release microsphere formulations of non-steroidal anti-inflammatory drugs (NSAIDs) administered via the intra-articular (IA) route is to minimise the systemic bioavailability and attendant side-effects associated with oral drug administration.
Macroalbuminuria was a strong predictor of eGFR loss and risk of developing sustained eGFR <60 ml/min/1.73 m.
A biphasic current with an initial peak and a slowly developing sustained phase is indicative for activation of CaCCs.
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More than most of Wilson's plays, "Fences" allows its performers to develop sustained one-on-one relationships.
"It is evident that the Bank of England wants to give the economy every chance to develop sustained broad-based growth with business investment increasingly contributing".
The Bank of England has made it clear that given the past extended weakness of the economy and the low base that growth is coming from, it wants to give the economy every chance to develop sustained, decent expansion.
The projects also try to develop sustained income-generating projects to pay for orphans' food, school fees and school uniforms, and for coffins to allow for dignified burials of family members.
Transgenic mice developed sustained anti-PrP titers, which were not suppressed by introduction ofPrnp + alleles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com