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Our findings are consistent with elevated SCN− contributing to an enhanced risk of developing pathologies associated with multiple inflammatory diseases.
Stress commonly suppresses immune function and chronic stress is typically associated with an increased risk of developing pathologies [ 34, 35].
This finding appears to confirm the fact that exposure to a hyperglycemic or hypoglycemic environment in the uterus leads to a common condition of reduced glucid tolerance at birth which tends to persist during growth and into adulthood and consequently to a higher risk of developing pathologies such as obesity and T2D.
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In general, a better understanding of the involvement of astrocytes in the developing pathology of Alzheimer's disease is of great importance for the future development of diagnosis and treatment.
A substantial body of evidence supports the notion that the development of a suppressive environment during chronic inflammation limits the success of immune-based and conventional therapies, skewing the balance in favor of a developing pathology.
Dr. Kinney was a prime mover in automation of the clinical laboratories, medical student teaching, and developing pathology manpower.
During the developing pathology, the marked border between the osteoblast growth zones and the chondrocytic areas connected to the arches became less distinct, as proliferating cells and chondrocytes blended through an intermediate zone.
Furthermore, examining effects at day 9 p.i. (prior to any evidence of clinical disease) and day 15 p.i. (after disease onset), highlighted the progression of gene changes that may be linked with developing pathology.
The degree to which those neurons develop pathologies varies, both in terms of whether disease development has to be induced by external stressors and the severity of those pathologies.
Although many individuals experiencing stressful events do not develop pathologies, stress seems to be a provoking factor in those individuals with particular vulnerability, determined by genetic factors or earlier experience.
In captivity, they often develop pathologies, such as the dorsal fin collapse seen in 60 90% of captive males.
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